All urine specimens should be collected by straight catheterization or suprapubic aspiration. Please document method of collection.
- Fever > 38.0 C (100.4 F) at home or by provider
- Toxic or moderately ill
Antimicrobial Dosing
ampicillin IV | 100 mg/kg/DOSE every 8 hours |
cefTRIAXone IV | 100 mg/kg/DOSE every 24 hours |
cefotaxime IV (alternative to ceftriaxone) | 50 mg/kg/DOSE every 8 hours |
acyclovir IV | 20 mg/kg/DOSE every 8 hours |
HOSPITALIZE
Start Empiric IV Antimicrobials:
- Ampicillin
- Cefotaxime or Ceftriaxone, and
- Acyclovir
If you have questions about any of the clinical pathways or about the process of creating a clinical pathway please contact the Clincal Pathway Oversight Committee at CPOC@montefiore.org.
Disclaimer: Clinical pathways are intended as a resource to guide diagnosis, treatment and management in order to improve quality of care and promote better patient outcomes. They are based on available medical evidence at the time of development; the date on the pathway indicates the most recent update. Pathways are not intended to provide medical advice or consultation regarding the care of any individual patient, and should not replace or supersede a practitioner’s professional opinion or clinical judgment. Because medical knowledge is constantly evolving, and accepting the possibility of error, The Children’s Hospital at Montefiore does not warrant or represent that pathways are complete or accurate. Neither the Hospital nor the individuals involved in the development or publication of the pathways is responsible for results or outcomes related to their use.
Collect:
- Blood: CBC w/diff, BCx, LFTs, glucose, CRP, HSV serum PCR (may send from floor)
- Urine: UA w/micro, Ucx
- CSF:
- culture and Gram stain,
- protein and glucose,
- cell count,
- HSV PCR (CSF), enterovirus PCR in season (June-October)
- RSV/flu if respiratory symptoms present
- CXR only if respiratory symptoms present
- Stool studies if diarrhea present
- HSV DFA or PCR if skin lesions present
Well appearing?
TOXIC OR MODERATELY ILL:
- Full sepsis work-up
- Start empiric anti-microbials
- Hospitalize
- If LP is deferred due to clinical instability, begin empiric antimicrobials and perform LP as soon as patient is stabilized
Corresponding EPIC Order Set:
- IP Peds Fever in Baby <29 Days Old
Consider discharge to home and further outpatient management after 36 hours if:
- Bacterial cultures are negative
- CSF HSV PCR is negative
- Good follow-up for serum HSV PCR (if pending) is assured
Criteria for Outpatient Management: (all must apply)
- Physician identified to assume outpatient follow-up at 24 hours
- Caregiver with good observation skills
- Telephone in home or a cell phone
- Access to PMD or ED within 30 minutes